History of Wuhan Institute of Virology and it's research on SARS-related corona viruses in 2015

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The Wuhan Institute of Virology, is a research institute on virology, that is administered by the Chinese Academy of Sciences (CAS), which reports to the State Council of the People's Republic of China. 

The institute is one of nine independent organisations in the Wuhan Branch of the CAS. It is located in Jiangxia District, Wuhan, Hubei. 

The institute has collaborated with the Galveston National Laboratory in the United States, the Centre International de Recherche en Infectiologie in France, and the National Microbiology Laboratory in Canada. 

The institute has been an active research center for the study of coronaviruses. 

History of Wuhan Institute of Virology.



The Wuhan Institute of Virology(WIV), was founded in 1956, under the Chinese Academy of Sciences (CAS). 

In 1961, it became the South China Institute of Microbiology, and in 1962, was renamed Wuhan Microbiology Institute. In 1970, it became the Microbiology Institute of Hubei Province, when the Hubei Commission of Science and Technology, took over the administration. 

In June 1978, it was returned to the CAS, and renamed Wuhan Institute of Virology.

Research on SARS-related coronoviruses.


In 2005, a group, including the researchers from the Wuhan Institute of Virology, published research into the origin of the SARS coronavirus, finding that China's horseshoe bats, are natural reservoirs of SARS-like coronaviruses. 

Continuing this work over a period of years, researchers from the institute, sampled thousands of horseshoe bats in locations across China, isolating over 300 bat coronavirus sequences.

In 2015, an international team, including two scientists from the institute, published successful research, on whether a bat coronavirus, could be made to infect HeLa.

(HeLa, is an immortal cell line, used in scientific research. It is the oldest and most commonly used human cell line.)

The team engineered a hybrid virus, combining a bat coronavirus with a SARS virus, that had been adapted to grow in mice, and mimic human disease. The hybrid virus was able to infect human cells.

The Institute contains the following research centers:

  • Center for Emerging Infectious Disease.

  • Chinese Virus Resources and Bioinformatics Center.

  • Center of Applied and Environmental Microbiology.

  • Department of Analytical Biochemistry and Biotechnology.

  • Department of Molecular Virology.

Thank you all!!!

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